What to do with a b&B i had booked?

Calculate the expected frequencies of the genotypes BB,Bb, bb. Please Help!!! :)?

  • Well I think I get how to do this but the question is: A four based cleavage site for the restriction enzyme BanI is located within a large intron of the larval transcript of the gene coding for alcohol dehydrogenase in Drosophila melanogaster. Cleavage at this site was found in 29 of 60 chromosomes ( that is, in 29/60 alleles) isolated from a population sampled at a market. Letting B and b represent the presence or absence, respectively, of the BanI site in a chromosome, and assuming Hardy-Weinberg genotype frequencies, calculate the expected frequencies of the genotypes BB,Bb, and bb.

  • Answer:

    Just base it on Hardy Weinberg, p+q=1 freq b = q freq B = p freq BB =psq freq Bb= 2pq freq bb=qsq and you know what p and q are because it basically tells you in the question, 29/60 = roughly 0.48 This is the value of p, to get the value of q just minus this from 1. off you gooooo!

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