What are similarities and differences between dynamic loading and late binding?

Pharmaceutics Help - $5 Amazon gift code?

• Can email answers at [email protected] Simethicone is most likely to be included in what type of OTC product? (A) antacid (B) cough product (C) decongestant (D) laxative (E) weight control Insoluble bismuth salts are used as adsorbents and also possess useful astringent and protec¬tive properties. A commercial product containing a bismuth compound is (A) Bisacodyl (B) Donnagel (C) Kaopectate (D) Pepto-bismol (E) Rheaban Which of the following antidiarrheal products contains the adsorbent clay attapulgite? I. Donnagel II. Kaopectate caplets III. Mitrolan Disadvantages of calcium carbonate as an antacid include all of the following EXCEPT (A) some patients may develop hypercalcemia (B) capacity for acid neutralization is poor*** (C) may cause constipation (D) may induce gastric hypersecretion (E) prolonged use may induce renal calculi and decreased renal function Which one of the following antacid products is a chemical combination of aluminum and mag¬nesium hydroxides? I. Basaljel capsules II. Rolaids chewable tablets III. Titralac chewable tablets Which one of the following antacid products is a chemical combination of aluminum and mag¬nesium hydroxides? (A) Gelusil (B) Maalox (C) Mylanta (D) Riopan (E) Tums Aspartame is included in some drug products as a (an) A) nutrient (B) vitamin (C) solubilizer (D) sweetener (E) stimulant Non-covalent interactions, Complexation and Protein Binding Next time you are in the pharmacy: Next time you are online: Homework questions 1. The three dimensional structure of a biological macromolecule (proteins, DNA and RNA) is determined by non-covalent forces. The precise structure of an enzyme active site is essential for performance of its catalytic function. The substrate of an enzyme usually binds in an active site via several simultaneous non-covalent contacts. Therefore, treat drugs composed of amino acids with kid gloves! Water-mediated interactions are often important in stabilizing ligand-receptor complexes. 2. Trying to keep a straight face, explain to your study buddy how you would employ the data contained in an isotherm to optimize characteristics of any dosage form of your choice. 3. When a substrate binds to an enzyme, the binding process sometimes results in the release of a bound water molecule. Why would this aspect of the process increase the stability of the enzyme-substrate complex? What implications does this have for the design of a pharmaceutical that could act as a competitive inhibitor of the natural substrate. 4. What similarities and what differences do you see in the nature of the binding of a penicillin to its therapeutic target (glycopeptide transpeptidase), compared to its binding to a protein (such as albumin) that sequesters the drug en route to its target. 5. Given data for free drug and bound over total protein answer: what is the protein binding constant of this drug with human serum albumin and estimate the number of binding sites for the drug. 6. Write a paragraph or two discussing the reasons that you feel protein binding is an important factor in drug therapy. 7. Purified water is obtained by more than one process, one of which your text calls the “Ion Exchange Method.” What similarity does the lecture notes share with this method used to arrive at the product Water for Injection USP? 8. The Universal Antidote is (supposedly) a mix¬ture of activated charcoal, magnesium oxide, and tannic acid. Does this make any sense? Why? 9. What is the mechanism of action of: Debrisan; Digibind 10. Which of the following antidiarrheal products contains the adsorbent clay attapulgite? Donnagel, Kaopectate caplets, Mitrolan. Where did you go to look that up? 11. What does not belong and why: technetium 99m, a radioisotope generator, pharmaceutical product labeled with a radioactive substance, ion-exchange column on which a nuclide has been adsorbed , high-energy-yielding radioactive isotope that produces one or more isotopes, emitting low-energy radiation, apparatus in which radioactive isotopes are incorporated into biologic molecules, cows. 12. List advantages/disadvantages of <ion exchange resins> is/are: 13. Suggest how a young intelligent pharmacist like yourselves can bring your understanding of isotherms to use in industry’s High Throughput Screening (HTS) strategy. 14. Sources of uncertainties in students of Christmas Past; perhaps you need to take a peek in Martin’s Physical Pharmacy for descriptions of the words. (Cool pictures, eh?) a. Hydrate vs. clathrate beta cyclodextrin vs.inclusion complex

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  Sorry, Mac - not even a $500 gift card is enough money for me to do your homework.