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Why does HCl dissolve in water?

Do I have to dissolve my 40MG Tablets of Methadone? Why am I not supposed to chew and/or swallow them?

  • I have been on methadone maintenance for about 3 years now & I just gained something called Step 30 which means that I don't have to go in to the clinic every day anymore. Instead, I come in once a month to pick up a months worth of pills. When I went in to the clinic I was getting liquid methadone, but now I have the Methadose 40mg Methadone Hydrochloride Tablets For Oral Suspension USP. On a different label they are also called Methadone HCL 40mg Diskettes. I'm told that I am not supposed to chew and/or swallow them before I dissolve them in water. Unfortunetly, they taste horrible and even mixing them in OJ is nasty. My question is, why can't I break them up & swallow them, & if I did what would be the worst thing that could happen? If I do absolutely have to dissolve them first, do you have any advice on a less painful way to administer them? Thanks!

  • Answer:

    I have had the liquid methadone & the wafers. I also had trouble drinking the dissolved solution. I experimented taking them in different ways & found that if you break them up into 1/4 pieces or 1/8 pieces & swallow them that you won't notice a difference between that & dissolving them.

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Reason why they say not to swallow them whole is because it will act like a Immediate release, Which is not the purpose of the diskettes. Its supposed to be mixed with a solution becuse it was made to get mixed with the solution and when you drink it, the acids in your stomach will dissolve the solution slowly,. acting more like a sustained release. since your doing a methadone maintenance, i would recommend you just dissolving in water.

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