What do you think of my hypothetical AIDS treatment? How could I design a research experiment?
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What do you think of my hypothetical AIDS treatment? How could I design a research experiment? I was given a research experiment for my Human Bio Class, an experiment where no actual physical experiment is done but conclusion is based on research. Anyway, I know that I have not found the cure for AIDS or anything but wrong or right I want to know your thoughts on my hypothesis and how could I design the experiment ( according to the scientific method of course). My hypothesis: We could quarantine a volunteer AIDS patient until all CD4 T-Cells dies off along with HIV virus, then we reintroduce previously copied copies of heallthy CD4 T-cells into the patient. The logic is that AIDS does not kill the patient, it is the "opportunistic diseases." So, we quarantine them until safe to reintroduce healthy CD4 cells. I know I could be totally wrong but constructive feedback and an experiment design would be appreciated. Thanks!
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Answer:
Sorry but the HIV virus would not just "die off" to the best of my knowledge, it would just keep making more and more of itself from the T cells that your body will keep producing, unless you can stop the body from producing any T-Cells. That's the inherent flaw in your design. However, to design an experiment I suppose your hypothesis would be that this procedure would restore the CD4 T-cells in the patient and restore normal immune functionality. Then have a group of patients you give the T-cells to and have a group you don't, and compare the T-cell counts at the beginning, end & at certain benchmarks of time (1 month, 6mo, 1yr etc) and check up on their progress to see if they regress. Good luck!
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Other answers
That actually could work. HIV replicates by using the T cells as the factories by which it uses the DNA of the T cell to make more genetic copies of HIV. The virus itself can't replicate because it doesn't have mitochondria. The only flaw is, you would have to keep them in total seclusion for a long time to kill off every T cell, or use a lot of radiation, and then if there were even one HIV cell alive, it could still duplicate and kill them. And if there was any contact with just one virus or bacterium, it could kill them.
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