What is the best thing to sell on ebay to make the biggest profit?

People aren't going to give you specifics - why should they set up another competitor? You want stuff at the liquidation level most of the time. ebay prices are too low for retail or wholesale to generate much profit. Try to find a niche that isn't being served well ( there are still some) and then find the best way to serve it.

The guy above is probably right. Nobody wants to create competitions by giving you their sources. I will however give you mine because I'm a wholesaler. I buy products by the pallets and custom pack them into an ebay start pack. I can give you link to those items that has been sold, so you know the average price on ebay and compare to the price I give you and see how much you profit. Contact me through my website if you are interested. Read the free ebay mini guide while you are there. go to http://www.cashvilleinfos.com and read the free guide that shows you how to make money on craigslist and ebay. I can tell you in a short cut that I can sell an item for 99 cents at a loss of profit on ebay, but I will make hundreds dollars off of those sells later. It's hard to explain the concept here though. Basicly you sell an ebook about some infos that you are good at (example how to play golf in 30 days) and then include a link to your website when you ship (email) the ebook (which is pdf file). Of course you provide golf related products on your website such as balls, clubs...ect...Chances are you will sell some items later when that person wanting to learn golf by buying your ebook golf guide. Now you save the ebay fees, listing fees and stuff so your webstore golf products will be cheaper than on ebay. That was just 1 method. I know tons of methods to make money online.

ANything you can buy from China for peanuts and resell for a fortune.

anything you can get cheaper. so buy in bulk and sell it cheap! and don't try to rip people off on shipping and handling!