Does any granulation occur in primary intention wound healing?

What is meant by primary intention healing and granulation?

• Can someone help me to answer this question. Thanks

• Answer:

  Primary intention healing is healing of a wound where the wound edges heal directly touching each other. This results in a small line of scar tissue, the goal whenever a wound is sutured closed. Granulation tissue is rapidly growing early scar tissue that has many blood vessels in it. This grows very fast, within hours to weeks of the wound. It's purpose is to fill in spaces in wounds where the edges are not directly apposed. After months, it turns into mature scar tissue, which has no blood vessels. In primary intent healing, the goal is to minimize the need for granulation tissue by holding wound edges tightly together. This way, scarring is minimized . Healing by secondary intent, on the other hand, may be the only possibility if the wound is infected or contaminated. In this case, the wound edges cannot be held together because the infection would grow in the space between. The wound is instead left open to fill with granulation tissue, and the granulation tissue will subsequently turn into scar tissue. This is not ideal, because scar tissue contracts significantly as it matures, often times resulting in cosmetic or disfiguring problems. However, if contamination or infection is bad enough, healing by primary intent may not be an option.