Can anyone explain the triplet code in simple terms?
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Answer:
It's a language just like English is a language. So let's do the comparison. English has 26 letters that make up words. DNA has 4 letters (bases). English sentences start with a capitol letter and end with a period. Messenger RNA starts with a "start" triplet and ends with an "end" triplet. English sentences are composed of words. The DNA sentence is a protein is is made of amino acids. English words can be any length of letters, but DNA words are only 3 letters long. There are an infinite number of words.... types of letters and length of words in English, but in DNA there are only 4 letters and words of 3 letters long. The words spell lots of things in English, but in DNA they spell amino acids. There are 20+ amino acids so how many words do we need? If each base was a word, and the words were 1 letter in size, it would only spell 4 amino acids..... too little. If the words were 2 letters long, then we would have 4 to the 2 power or 16 types of words..... too little to spell the 20+ amino acids. If words were 3 letters long (4 to the 3rd power) we would have 64 words.... too many but that's not a problem if more than one word spells an amino acid. Words intelligently placed in a sentence makes a thought. Triplet code words in the DNA sequence produce a protein.
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Other answers
It's a language just like English is a language. So let's do the comparison. English has 26 letters that make up words. DNA has 4 letters (bases). English sentences start with a capitol letter and end with a period. Messenger RNA starts with a "start" triplet and ends with an "end" triplet. English sentences are composed of words. The DNA sentence is a protein is is made of amino acids. English words can be any length of letters, but DNA words are only 3 letters long. There are an infinite number of words.... types of letters and length of words in English, but in DNA there are only 4 letters and words of 3 letters long. The words spell lots of things in English, but in DNA they spell amino acids. There are 20+ amino acids so how many words do we need? If each base was a word, and the words were 1 letter in size, it would only spell 4 amino acids..... too little. If the words were 2 letters long, then we would have 4 to the 2 power or 16 types of words..... too little to spell the 20+ amino acids. If words were 3 letters long (4 to the 3rd power) we would have 64 words.... too many but that's not a problem if more than one word spells an amino acid. Words intelligently placed in a sentence makes a thought. Triplet code words in the DNA sequence produce a protein.
DrJ
There are four bases total that RNA can use when it copies a gene: A,G,U,C. There are 20 amino acids that can be put into a protein. Think of the phrase "coding for" to mean you are coding (or decoding) a secret message, like in "National Treasure" or "The DaVinci Code". If you just used single letters to code for each protein, you could only code for 4 amino acids... (A = amino acid #1, G = amino acid #2, etc). Since there has to be a way to code for all twenty, try making pairs of letters match up to amino acids. (AG = amino acid #1, AU = amino acid #2, AC = amino acid #3, etc). But that would still only give you 8 different combinations, which is still short of the at least 20 we need. Ok, since single letters and pairs don't work, how about triplets? Arranging the 4 letters (A,G,U,C) into triplets gives you 64 different possible combinations, and those are called codons. That is way plenty to code for the 20 amino acids. It's actually enough to code for each one three different ways! That's why the code uses triplets. In actuality, some amino acids still only have one triplet that codes for them and others have several. In fact, only 61 of the 64 codons actually code for amino acids. The three left over signal that the chain is finished and are called "STOP codons"
Laura N
for u.. from zero level to top. the RNA have base pairs i.e A U G and C, the when process of conversion of genetic code to proteins takes place the tRNA reads these A U G C sequence in pair of three and form a amino acid, and continues till it gets the code for stop. i.e UGA. so when tRNA form an amino acid from mRNA sequence it reads three base pairs at a time, triplet code.. thank u.. :)
hot shot
In mRNA, there are four types of bases. Among them, at least three nucleotide residues are required to code for each amino acid. This genetic code words or codons (of three nucleotide residues) is referred to as triplet codon.
Sarowar
There are four bases total that RNA can use when it copies a gene: A,G,U,C. There are 20 amino acids that can be put into a protein. Think of the phrase "coding for" to mean you are coding (or decoding) a secret message, like in "National Treasure" or "The DaVinci Code". If you just used single letters to code for each protein, you could only code for 4 amino acids... (A = amino acid #1, G = amino acid #2, etc). Since there has to be a way to code for all twenty, try making pairs of letters match up to amino acids. (AG = amino acid #1, AU = amino acid #2, AC = amino acid #3, etc). But that would still only give you 8 different combinations, which is still short of the at least 20 we need. Ok, since single letters and pairs don't work, how about triplets? Arranging the 4 letters (A,G,U,C) into triplets gives you 64 different possible combinations, and those are called codons. That is way plenty to code for the 20 amino acids. It's actually enough to code for each one three different ways! That's why the code uses triplets. In actuality, some amino acids still only have one triplet that codes for them and others have several. In fact, only 61 of the 64 codons actually code for amino acids. The three left over signal that the chain is finished and are called "STOP codons"
Laura N
for u.. from zero level to top. the RNA have base pairs i.e A U G and C, the when process of conversion of genetic code to proteins takes place the tRNA reads these A U G C sequence in pair of three and form a amino acid, and continues till it gets the code for stop. i.e UGA. so when tRNA form an amino acid from mRNA sequence it reads three base pairs at a time, triplet code.. thank u.. :)
hot shot
In mRNA, there are four types of bases. Among them, at least three nucleotide residues are required to code for each amino acid. This genetic code words or codons (of three nucleotide residues) is referred to as triplet codon.
Sarowar
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