How can i get mildew off leather jacket vest (its geniune leather) i need to do it at home

Mildew and mold can be a problem on leather. The mold spores will have to be killed otherwise the problem will simply keep happening. Mold residues can be cleaned from the surface of leather with most standard leather cleaners but they will come back again if the problem has not been dealt with. You need to use an enzyme cleaning product that has been tested on leather and will not damage the finish. Try LTT Em Clean which has been fully tested on leather but can also be used on fabrics. Mold spores that have been left on leather for some time may cause pitting in the leather which would need to be repaired http://www.lttsolutions.net/em-clean.asp

Mildew that is not real bad can often be removed with soapy water. Diluted Alcohol with water may also help, but can dry out the skin. A good leather conditioner may be applied once the vest is dry. Look into what caused the mold to occur. Was the vest improperly stored? Consider having it professionally cleaned to fully remove the mold.