How common is down syndrome?

How common is Marfan syndrome in the general population?

• Answer:

  How Common Is Marfan Syndrome? According to the National Marfan Foundation - Marfan.org - 1 in every 5,000-7,000 babies born is a child with Marfan syndrome. Other statistics about Marfan syndrome 75% of people with Marfan syndrome have an affected parent. Approximately 25% of all cases are due to de novo (spontaneous) genetic mutations. This means they are the first person in their family to be affected. Marfan syndrome is an autosomal dominant mutation; this means that, if the mutation is present, the person has the syndrome to at least a mild degree. It can not skip generations. A person with Marfan has a 50% chance of passing it on to their children. Estimates indicate that approximately 0.02% of the global population has Marfan syndrome. Marfan syndrome is found equally in all ethnicities.