Find solution
What is the difference between Computational Biology & Bioinformatics?

What are different research areas available for Bioinformatics?

  • I'm an undergraduate student studying biotechnology from one of the old IIT's. We're started with bioinformatics topic recently and covered just the sequence alignment part. So, I wanted to know how exactly the projects in this field are and what is the scope for this field? I'm more interested to listen to projects rather than the scope. Does it involve working with computers only? Secondly, what is the difference between Bioinformatics and Computational Biology (in projects) I would very much appreciate it if someone elaborates about the projects in both the fields.

  • Answer:

    Bioinformatics is an interesting and most exciting field as far as the biological research is concerned. Bioinformatics deals with solving the problems of Biology using Computers . The projects in bioinformatics aim at solving a biological problem. With the advent of modern sequencing technologies like the automated sequencing method, there is a surge in  the data generated using  these experiments. This problem of data storage can be addressed by developing databases by amalgamating the knowledge and principles of Both Computer Science and Biology, Data of micro array experiments are stored in Array Express, Gene Expression Omnibus and other databases.   The problem of drug designing can be addressed by using various algorithms that can be used to simulate the life processes of a cell. The Protein ligand binding is simulated in docking studies. There are Software that predict the ADME properties of drugs etc. These Software can be used to reduce the time required for designing a drug. Also many Metabolic Pathways can be simulated using matlab. Coming to the second part of the Question. Both Bioinformatics and Computational biology are intertwined where the former deals with developing methods for storing, retrieving, organizing and analyzing biological data. and the later deals with the application of  mathematical modeling and computational simulation techniques to the study of biological, behavioral, and social systems.

Vishnutheja Reddy at Quora Visit the source

Was this solution helpful to you?

Other answers

Hello,i just completed my engineering in this field this year,and no i did not do my final semester project in core bioinformatics,it was in analytical chemistry coupled with a little bioinformatics. Yes it involves working with computers most of the time and doing a lot of database searching,contructing of metabolic pathways,algorithm development. If you look for projects,they will mostly involve CADD(computer aided drug designing) and scripting (bioinformatics) and computaional biology will involve subjects like systems biology,thermodynamics coupled with MATLAB. As you have stated that you have just finished with sequence alignment,that is one of the very basic and the first steps and very interesting too.There are some research centers and companies which help us with projects,you can inbox me for more details.

Anonymous

Thanks for A2A,I would rather scribble it hear point you out to my previous answers concerning the field and if you find them convincing for you that would be amazing and also pleasing to me as well.The above the posts have good answers and also answers written by me and should be pretty detailed and informative enough for you to get an understanding of the field and how different aspects work. Most of my answers are related to next generation sequencing and its usage in field of precision medicine and personalised medicine but having said that it might trigger a bit of interest in you as well. One of my favourite answer is the below. Hope you enjoy it.

Vivek Das

Related Q & A:

Just Added Q & A:

Find solution

For every problem there is a solution! Proved by Solucija.

  • Got an issue and looking for advice?

  • Ask Solucija to search every corner of the Web for help.

  • Get workable solutions and helpful tips in a moment.

Just ask Solucija about an issue you face and immediately get a list of ready solutions, answers and tips from other Internet users. We always provide the most suitable and complete answer to your question at the top, along with a few good alternatives below.