Vacationing in New York, Manhattan, what is the best airport to fly into and best way to get to hotel?

LaGuardia is the closest physically. JFK is a little easier to get to by transit. Depending on how much luggage you have, I'd say either the subway or shuttle is best. From LGA, you'd have to take the Q33 or Q47 to Jackson Heights and then take the Manhattan-bound (E). From JFK, you'd have to take the AirTrain to Jamaica for the Manhattan-bound (E). Get off at 5th Avenue or 7th Avenue, depending on which is closer.

Laguardia is the closest , most of the major hotels have a shuttle bus that is free or very low cost you call the hotel when you get your luggage some hotels have their courtesy phones at the airport , otherwise keep the hotel number in your wallet so as to call them on your cell phone . If your hotel does not have a shuttle then a cab or limo would be the next choice because schlepping luggage on a city bus or subway is a real chore .

La Guardia Airport is the nearest; it will be quite convenient for you to travel by this place. There are luxury hotels that are nearby this famous airport that you can reach comfortably. You can hire Airport limousine in the area to reach airport in time. These days’ airport limousines are easily available. Last month, I hired airport limousine from Michael’s limousine to drop me to my desired place. They really offered me stylish limousine with a quite friendly limo chauffeur who cared for all my travel needs. They assisted me to carry my luggage to and from airport. So this time use their service, they will drop you to your designated place in time. I am sure that you will easily get one limousine that suits your budget with them.

LaGuardia Airport is closer to 54th street. Do Not take the Subway trust me it won't be a pleasant ride, so it's better to take a cab because the shuttle might be crowded.