How do you study a study?
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How can a layperson find out if a study has been discredited, or else disputed? I've been reading several (non-fiction) books lately where this is the underlying theme: Study X is performed and is flawed for many reasons, but its conclusions are either intuitive or shocking or politically expedient at the time it was conducted; it gets repeated over and over until it's "fact" in a discipline to the extent that questioning it will get you laughed at, even though other experiments are showing something isn't quite right; just within the past decade or two decades there's been a ton of research proving the study's conclusions are wrong so now the public is hearing conflicting information but has no idea what to believe, but the media/government/academia hasn't entirely caught up yet because there are too many things for people to keep up with, or the media and government are unknowingly pushing outdated science and it's hard to overcome this, or there are a bunch of stubborn academics who refuse to accept the old study was wrong, or (very often) people are so specialized academically that they have to spend all their time keeping up with the developments in their narrower field and miss out on things in related fields that could be vital, etc. The bottom line is something is wrong, and the information exists, but people don't know it's wrong because they don't have the information. That this happens is unfortunate but seemingly inevitable, and that's easy to accept. However, it makes it difficult for a layperson to make sense of the conflicting information. Sometimes there's literally no way for a layperson to figure out what might have gone wrong, and sometimes it's even difficult for a specialist in the field to figure it out. For example, one study I read about made some outrageous claims about (iirc) the drug ecstasy literally eating through your brain, but it was never able to be replicated even by the same researcher, and later it was revealed that what probably happened was the lab the researcher got the ecstasy from accidentally gave him a different chemical that did produce those results. The brain scans from that study still appeared on government anti-drug websites for years and years after the study was discredited. I remember seeing those same brain scans in my DARE classes as a child. However, if I hadn't happened upon this book that was about scientific missteps and the author hadn't been a scientist who made a point of figuring out precisely what happened, I would have never known that study was discredited. I assume that the majority of people who were exposed to its conclusions don't know it was discredited. So my question is this: if a layperson is reading a book or article and a specific study is mentioned, what resources are available to them that will allow them to see if a study has been discredited or disputed? It's difficult enough for a layperson to access studies as it is, and that's only helpful if you want to look at the methodology or see if their conclusions match the results. But for something like the above, how is anyone supposed to know that study has been discredited? If you pull up a copy of the study, it's not going to have a big red "DISCREDITED" stamp on it. If you've cited the study before, no one automatically mails you updates about it; the government didn't even realize it had been discredited. Books that really break these things down are helpful, but hard to find. "The internet" is an answer, but it's too broad for what I'm asking for. Is there a place that keeps track of developments that happen to a particular study after a study is published? Are there particular websites that are better for looking up this sort of thing than others? Is there a secret Google-fu manueuver that will get better results? Any resources that are particular to certain disciplines? Similarly, what are the easiest ways for a layperson to get access to the text of studies? Every time I've tried it's been a hassle; so many online sources are pay only, and it's difficult to find most of the journals at a regular library because there are so many of them now.
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Answer:
Following up Maias comment, Peter Norvig's article http://norvig.com/experiment-design.html is a good overview of common problems to look for when reading research.
Nattie at Ask.Metafilter.Com Visit the source
Other answers
I agree with most of the advice here, but there are a few other things you should consider. Your view of new studies coming out and completely discrediting another isn't that accurate. Science is about an accumulation of knowledge and deciding which way the evidence leads. There are times when a study is retracted (eg. for http://docs.google.com/viewer?a=v&q=cache:ewfdV87KEFcJ:press.thelancet.com/wakefieldretraction.pdf+lancet+retracted+article&hl=en&gl=ca&pid=bl&srcid=ADGEEShmohPj_UHJsv724vDO36T4IN1slgKGEAC3cUQtWNMa1rACN4SnrfGHnUSszz7UY9ttbB1-vLFqeHK9IX1Bonr_zly_CnVw5FEF-olgh44tMSabQ7mA1G97J3Ay1_tY6c0x4MOm&sig=AHIEtbQI4TSPSWqHsNXNLCnNhYcYBr46NA), you can watch for journals to put out notices like this, however this is rare. To get a better view of a subject, you might want to look at review articles or http://en.wikipedia.org/wiki/Metaanalysis. The latter is a study that pools data from a number of previous studies, while the former is a peer-reviewed summary by a specialist on a particular subject. For medical studies, for example, http://www2.cochrane.org/reviews/ are often held in high regard.
Midnight Rambler
Is there a place that keeps track of developments that happen to a particular study after a study is published? No. Are there particular websites that are better for looking up this sort of thing than others? No. Is there a secret Google-fu manueuver that will get better results? Any resources that are particular to certain disciplines? Other than "[terms from original study] disconfirm" or related terms like discredit or wrong etc, no. what are the easiest ways for a layperson to get access to the text of studies? Go to a university library.
ROU_Xenophobe
Not quite what you're asking but I have a site http://sciencerumors.org/ which I'm setting up to collaboratively gather and rank information about scientific studies. Basically my goal is for the layperson to have a place to go and learn/debunk/research, and for it to act as a filter where you can see only the studies that are already verified to some extent or other. I'm planning to do most of this based on metadata about the study, its publication, its methodology, etc. I also want to track whether it's a confirmation or refutation of an earlier study/theory, or purely new data. Your desire to look at a study and see what later studies have affected its usefulness is cool and while it's not the focus of the site I'll have to make sure to do it as much as the data we're gathering allows. Unfortunately it's a placeholder site still but I'm committed to getting it rolling soon. If anyone would like to be contacted once I've got it rolling, or would like to get involved please do let me know.
vsync
One thing you could do is look into which journal published the paper. Some journals are known for being the best, everything they publish is rigorously peer reviewed and they also publish letters to the editor from other experts in the field giving their opinion on the study after the fact. These journals also require anything published in them have a thorough limitations discussion, in which the authors admit and describe every last thing that could possibly be un-perfect with the study and how it could alter the conclusions... then there are journals who have a reputation for publishing just about anything. I have myself (along with many colleagues) published scientific literature and there is definitely a list we will go down... try to get it published with Journal A, if they don't accept it, move down to Journal B and so on. No study is perfect. You could find the best designed study in history and still pick it apart and question it's conclusions. Ideally, become well-versed in study design and read the study yourself! as others have mentioned, University libraries will have them.
Carol@ILPoisonCenter
(and 'significant' in science means a very specific thing: that the results have been statistically examined and that the reported relationship is only 5% (or whatever the level of statistical significance being used is) likely to have occurred by chance) Not to pick on you, damonism, but "statistically significant" does mean a very specific thing, and that is not it. In the case of a significance level of 0.05, it means that the results as large or larger or larger than the reported results are 5% likely to occur if the null hypothesis is true. This is a very common error, currently listed as #2 on the http://en.wikipedia.org/wiki/P-value#Frequent_misunderstandings of the p-value in Wikipedia. In http://news.sciencemag.org/sciencenow/2009/10/30-01.html with Harvard biostatistics chair Victor De Gruttola ("passionate about his p-values") says about this error, "It's not that. It's really not like that. It's the difference between I own the house or the house owns me. It's two different concepts." In other words, your formulation is P(H0 | D = data) but p is actually P(D ≥ data | H0). The former seems more like something that would be more useful to measure but it is impossible with the frequentist statistical framework used in classical hypothesis testing.
grouse
We have a guide to deciding when to change your behavior based on new medical research at stats.org http://www.stats.org/in_depth/evaluate_healthrisks/How_eval_health_risks.htm. The rest of the site also has resources that may be helpful in evaluating research claims.
Maias
Thanks again everyone, I appreciate all these answers. And vsync, hell yes I would love to be contacted when you get it rolling; that sounds like a cool idea!
Nattie
You can search http://scholar.google.com for the article of interest, and then click the "Cited by" link. Also, the relevant page on the journal's website is likely to have a similar link. There was a http://ask.metafilter.com/136367/Where-can-I-get-affordable-online-access-to-academic-journals about finding copies of journal articles online.
James Scott-Brown
Not to pick on you, damonism, but "statistically significant" does mean a very specific thing, and that is not it. I stand corrected then. In my defence, it has been 14 years since I last took a statistics course :-)
damonism
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