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When is a single base substitution mutation least likely to be deleterious?

Can you explain the effect of base substitution mutation in sickle cell anemia

  • Answer:

    In a single base mutation, a single base, say an A, simply becomes replaced by another. Single base substitutions are also called point mutations.

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In a single base mutation, a single base, say an A, simply becomes replaced by another. Single base substitutions are also called point mutations.

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