What is the best desktop publishing program to use to create an online magazine?

First Bob's suggestions are very good. I am a Linux user, though my additions will be mostly OS-agnostic. It does make me hostile to Adobe right now. I used to get paid to use a mac for graphics now and then. I never got paid enough to buy one and so the jobs dried up. Adobe has gone beyond not supporting Linux to a policy of using drm and such which actively interfere with my OS. It happens they have caused problems on other OSes and I've a few times recommended the program InDesign has largely supplanted: http://www.quark.com/Products/QuarkXPress/ and either made new satisfied customers or reinspired old ones. They also don't support Linux they just don't cut corners the way Adobe has been lately. The other alternative is that MOST Office Suites, are quite able to produce magazines. Including Office, OpenOffice.org or my preferred one Libreoffice. Here is a magazine which covers it: http://libregraphicsmag.com/